PROFHILO Bioremodelling Injectable HA

About the treatment

PROFHILO product images

The first of its kind, PROFHILO is a unique, heat stabilized, bioremodelling injectable HA for the skin. This is an innovative injectable treatment, powered by IBSA Italia’s NAHYCO Technology, allowing the treatment to give positive, visible results after only 2 treatments, done 4 weeks apart.

As we age, our skin starts to sag and skin laxity develops soon after. This is brought about by the breakdown of our intrinsic collagen and elastin within our skin dermis. Studies have shown that the NAHYCO technology behind PROFHILO is effective in stimulating the production of all 4 types of collagen present in our skin. This makes it a truly effective skin rejuvenation treatment.

the face of female model exuberate with radiance after using Profhilo singapore

What are the benefits of the treatment?

PROFHILO has been shown to provide the following benefits in multiple clinical studies

  1. Restore up to 4 types of collagen molecules (Types I, III, IV and VII) within our skin
  2. Hydration effect given by low molecular weight HA (L-HA)
  3. Firming effect given by high molecular weight HA (H-HA)
  4. Leading to firmer and more supple skin
  5. Treatment of fine lines and wrinkles (static wrinkles)
  6. Improves dry, aged skin to a healthier, and more hydrated one
PROFHILO product features

A Unique and Safe skin enhancing treatment

Though Profhilo is a very new product in the Singapore market, it has been around in Europe (its initial market) for a number of years, and has established a sizeable number of studies that support its safety profile:

Highest HA concentration.The HA content in PROFHILO is 64 mg/2mls of prefilled syringe. This is the highest HA concentration that currently exist in the market. This characteristic allows it to give maximal hydration effects to the skin.

Non-BDDE cross linking. This decision reduces the risk of lumps and allows it to have high spreadability within the dermis compared to other injectable HA.

Heat stabilized. PROFHILO utilizes a proprietary heat stabilization process in its manufacturing. This allows the HA complex to be retained longer within the treatment areas to exert its effects. The hybrid HA complexes has been shown to last more than 8X versus other non-cross linked HA products.

Difference between PROFHILO HA, HA Filler, and HA Skinbooster?

Though all three types of treatments contain hyaluronic acid (HA), the chemical structure and how they are manufactured give them different advantages in different treatment scenarios.

Facial sculpting, choose HA filler: HA fillers are the preferred option to replace loss facial volume in specific regions like cheeks, nasolabial folds, and improve facial contours like enhancing chin shape and sunken temples.

Skin hydration, choose HA skinbooster: these skinbooster treatments contain HA in its low molecular weight forms, and are injected at multiple points in the skin. Downtime can be a few days to perhaps a week, and one important downside is that most HA skinbooster treatments require frequent treatment sessions (once every 3-4 weeks) as the results are short-lived.

Skin tightening with optimal hydration, choose PROFHILO: with its NAHYCO hybrid complexes containing both low and high molecular types of HA, PROFHILO is a unique product that does both hydration and skin tightening. PROFHILO stimulates production of 4 subtypes of collagen and elastin that are found in our skin, bringing about smoother, tighter skin with increased hydration and radiance.

Frequently Asked Questions

PROFHILO is suitable for anyone who is in their late twenties and above who are experiencing issues of skin laxity or dehydrated skin. This treatment has no upper age limit. In fact, patients with more skin laxity will generally see more dramatic results. 

We however, will not perform PROFHILO treatment for the following groups of patients: 

  • Pregnant women
  • Breastfeeding mothers
  • Known hypersensitivity reactions to hyaluronic acid
  • Immunocompromised individuals
  • Cancer

Profhilo is an effective standalone treatment that gives hydration and visible skin firming effects. However, we need to emphasise that this is not a facial augmentation procedure using dermal fillers. You will not be able to see changes in your facial contour. To enhance your facial features and contours, you can read more about our Dermal Filler treatment with Juvederm.

PROFHILO is a versatile injectable treatment that can be combined synergistically with energy- based devices like Lasers, High Intensity Focused Ultrasound Devices (HIFU), Thermage, etc.

The treatment is done using a fine needle to deposit the PROFHILO hybrid HA complex in the dermal layer of the skin, through a series of micro-injections. For face treatment using PROFHILO, a unique injection protocol known as the Bio- Aesthetic Points (BAP) is employed. This injection technique has been developed by BSA Italia, the developer and manufacturer of PROFHILO. In this protocol, only 5 injection points on each side of your face is required.

The treatment alone will take only 15-20 minutes.

Anesthetic cream will be applied on target areas of treatment prior to the treatment itself to minimize any pain or discomfort Finally, the micro-injections are done through ultra-fine needles, making procedure is comfortable. You will be able to go through it with ease. 

After the injection, there will be visible bumps on the skin. These bumps will disappear within 24 hours due to the easy spreadability of PROFHILO. You may also experience some swelling and bruising. These side effects will be temporary as well.

Most will observe a visible hydration effect on the skin, as early as a few days after the first treatment. The firming and skin tightening effect of PROFHILO is brought about through bio-remodelling with the stimulated production of the various collagen subtypes. It is usually evident after the second treatment, and improves over the next 2-3 months.

For a treatment region (e.g. face or neck), a full procedure consists of a total of 2 treatment sessions. The second treatment session is repeated 4 weeks after the initial treatment. The overall result lasts approximately 6 months, after which the full procedure can be repeated.

Yes, other body parts that are suitable to undergo PROFHILO treatment include:

  1. Neck
  2. Décolletage
  3. Hands
  4. Upper arms
  5. Knees
  6. Other areas of visible skin laxity may be suitable for treatment after thorough assessment with doctor
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