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A Polynucleotide (PN) Skin Booster is an advanced injectable treatment designed to regenerate and repair the skin at a cellular level. Polynucleotides are naturally derived DNA fragments that stimulate tissue repair, boost collagen and elastin production, and improve skin health from within.
Unlike hyaluronic acid skin boosters, which primarily focus on hydration, PN Skin Boosters go a step further by actively encouraging skin healing and regeneration. This makes them particularly effective for improving skin texture, firmness, and overall vitality.
PN Skin Boosters are highly versatile and suitable for a wide range of concerns, including:
PN Skin Boosters are ideal if you are seeking not just hydration but also regeneration and repair. They are especially suitable for:
Individuals noticing early signs of skin ageing
Patients with dull, tired, or sun-damaged skin
Those with mild acne scarring or uneven texture
People who want firmer, smoother, and healthier skin without drastic changes to their features
A consultation is recommended to assess your skin and determine the most appropriate treatment plan.
Small amounts of polynucleotides are injected into the superficial layers of the skin using fine needles, allowing the active ingredients to work at a cellular level.
Most patients find the procedure well-tolerated. A topical numbing cream can be applied to minimise any discomfort.
Each session takes around 20–30 minutes, depending on the treatment area.
A series of 3–4 sessions spaced a few weeks apart is typically recommended for optimal results, followed by maintenance treatments every 6–12 months.
Improvements develop gradually as the skin begins to repair and regenerate. Patients often notice firmer, brighter, and more youthful-looking skin in the weeks following treatment, with continued improvement over time.
Yes. PN Skin Boosters can be combined with other aesthetic procedures to enhance overall results. They pair particularly well with:
For reducing expression lines alongside improved skin quality.
To restore lost volume while PN Skin Boosters regenerate skin.
To target pigmentation and sun damage in combination with skin regeneration.
For enhanced collagen stimulation and repair.
| Feature | HA Skin Booster | PN Skin Booster | Dermal Filler |
| Main Purpose | Deep hydration & improved skin quality | Skin regeneration & repair at cellular level | Restore lost volume & contour facial features |
|---|---|---|---|
| How it Works | Micro-injections of hyaluronic acid to boost hydration and elasticity | Polynucleotides stimulate tissue repair, collagen & elastin production | Gel-like filler adds volume, smooths wrinkles, and enhances structure |
| Best For | Dry, dull, tired-looking skin; fine lines; uneven texture | Fine lines, loss of firmness, scarring, sun damage, overall regeneration | Volume loss, deep wrinkles, contouring (cheeks, lips, jawline, chin, tear troughs) |
| Treatment Areas | Face, neck, décolletage, hands | Face, neck, décolletage, hands | Face (cheeks, lips, jawline, chin, tear troughs) |
| Key Benefits | Hydrated, glowing, smoother skin | Firmer, more resilient skin with long-term repair | Immediate restoration of volume & definition |
| Results Visible | Gradually, within a few weeks | Gradually, improving over weeks to months | Immediately, with final results after swelling settles |
| Longevity | 6–12 months | 9–12 months | 9–18 months |
| Sessions Required | 2–3 sessions, then maintenance | 3–4 sessions, then maintenance | Usually one session, with top-ups as needed |
| Combination Options | Pairs well with botulinum toxin, fillers, lasers, microneedling | Pairs well with botulinum toxin, fillers, lasers, microneedling | Pairs well with botulinum toxin, skin boosters, lasers |
| Price | From $1200 | From $800 | From $908/ml |
Results typically last between 9 to 12 months, depending on your skin condition, lifestyle, and maintenance treatments.
You may experience mild redness, swelling, or small bumps at the injection sites, which usually resolve within 24–48 hours. Most patients return to normal activities immediately.
HA Skin Boosters primarily restore hydration, whereas PN Skin Boosters focus on regeneration and repair at a cellular level. Many patients benefit from alternating or combining both treatments for maximum results.
Yes. PN Skin Boosters are derived from highly purified DNA fragments and are biocompatible, making them safe and well-tolerated for most patients.
A course of 3–4 treatments is generally recommended, with maintenance sessions every 6–12 months.
Some patients notice improvements within a few weeks, but the regenerative effects continue to build over several months, with optimal results seen after the full treatment course.
